C2orf49

Across TCGA patient cohorts, C2orf49 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,688 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C2orf49-associated proteins across cancer lineages are WRNIP1, YTHDC1, and GATAD2B. Each is linked with C2orf49 in more than 4 cancer types. Because this analysis shows association rather than direction, both C2orf49-to-partner and partner-to-C2orf49 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2orf49 versus WRNIP1 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf49→partner) and Y-score (partner→C2orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WRNIP1 →	+0.360	+0.350	<.001	<.001	3	5
HNSC	YTHDC1 →	+0.254	+0.668	.001	<.001	3	5
HNSC	GATAD2B →	+0.305	+0.582	.001	.003	3	5
LSCC	SAE1 →	+0.226	+0.369	<.001	<.001	3	5
LSCC	SSB →	+0.309	+0.450	<.001	<.001	3	5
OV	TSN →	+0.384	+0.531	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,688 associations by consensus.

C2orf49 vs WRNIP1 — LSCC

Explore this scatter interactively →