C2orf49

Across TCGA patient cohorts, C2orf49 protein abundance is significantly associated with the RNA expression of many other genes, with 17,052 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C2orf49-associated genes across cancer lineages are CENPO, RPIA, and LRPPRC. Each is linked with C2orf49 in more than 5 cancer types. Because this analysis shows association rather than direction, both C2orf49-to-partner and partner-to-C2orf49 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2orf49 versus CENPO in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf49→partner) and Y-score (partner→C2orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CENPO →	+0.834	+0.239	<.001	<.001	3	6
HNSC	RPIA →	+0.910	+0.233	<.001	<.001	3	6
HNSC	LRPPRC →	+0.931	+0.272	<.001	<.001	3	6
HNSC	MSH2 →	+0.812	+0.237	<.001	<.001	3	6
HNSC	ATIC →	+0.799	+0.188	<.001	<.001	3	5
HNSC	SNRNP200 →	+0.830	+0.249	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,052 associations by consensus.

C2orf49 vs CENPO — HNSC

Explore this scatter interactively →