C2orf49

Across TCGA cell cohorts, C2orf49 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,205 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C2orf49-associated GO terms across cancer lineages are Positive regulation of mRNA metabolic process, Positive regulation of mRNA catabolic process, and tRNA splicing, via endonucleolytic cleavage and ligation. Each is linked with C2orf49 in more than 11 cancer types. Because this analysis shows association rather than direction, both C2orf49-to-partner and partner-to-C2orf49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA metabolic process grouped by C2orf49-low versus C2orf49-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf49→partner) and Y-score (partner→C2orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of mRNA metabolic process →	+0.075	+0.795	.007	.003	3	12
STOMACH	Positive regulation of mRNA catabolic process →	+0.066	+0.754	.008	.006	3	12
BREAST	tRNA splicing, via endonucleolytic cleavage and ligation →	+0.099	+0.690	<.001	<.001	3	12
BLOOD_Lymphoma	Regulation of translational initiation →	+0.061	+0.604	<.001	<.001	3	12
BLOOD_Lymphoma	Protein modification by small protein removal →	+0.045	+0.760	<.001	.001	3	12
BLOOD_Lymphoma	Cytoplasmic translation →	+0.078	+0.872	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,205 associations by consensus.

Positive regulation of mRNA metabolic process by C2orf49 expression — STOMACH

Explore this box plot interactively →