C2CD6

Across TCGA patient cohorts, C2CD6 mutation is significantly associated with the RNA expression of many other genes, with 4,403 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2CD6-associated genes across cancer lineages are ZNF677, TRAJ21, and LINC02641. Each is linked with C2CD6 in more than 2 cancer types. Because this analysis shows association rather than direction, both C2CD6-to-partner and partner-to-C2CD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF677 grouped by C2CD6-low versus C2CD6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD6→partner) and Y-score (partner→C2CD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF677 →	-0.353	-1.280	.002	.002	3	3
UCEC	TRAJ21 →	+0.223	+1.437	.004	.001	3	3
CESC	LINC02641 →	+0.405	+3.902	<.001	.001	3	3
UCEC	ATP5MG →	+0.315	+1.490	<.001	<.001	3	3
UCEC	GPX4 →	+0.272	+1.124	.005	.001	3	3
UCEC	RABEPK →	+0.244	+1.230	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,403 associations by consensus.

ZNF677 by C2CD6 expression — UCEC

Explore this box plot interactively →