C2CD6

Across TCGA cell cohorts, C2CD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,623 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C2CD6-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of myoblast fusion, and Endosomal transport. Each is linked with C2CD6 in more than 8 cancer types. Because this analysis shows association rather than direction, both C2CD6-to-partner and partner-to-C2CD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by C2CD6-low versus C2CD6-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD6→partner) and Y-score (partner→C2CD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of myoblast fusion →	+0.094	+0.195	<.001	.008	3	9
URINARY_TRACT	Regulation of myoblast fusion →	+0.094	+0.394	<.001	.006	3	8
OVARY	Endosomal transport →	+0.034	+0.348	.008	.007	3	8
BLOOD_Myeloma	Establishment of protein localization to membrane →	+0.040	+0.040	.004	.001	3	8
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.085	+0.030	<.001	<.001	3	7
BONE	Golgi vesicle transport →	+0.060	+0.642	.001	.004	1	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,623 associations by consensus.

Negative regulation of myoblast fusion by C2CD6 expression — PANCREAS

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