C2CD6

Across TCGA cell cohorts, C2CD6 mutation is significantly associated with the RNA expression of many other genes, with 141 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2CD6-associated genes across cancer lineages are TSPAN16, PNLIPRP3, and OR13C3. Each is linked with C2CD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD6-to-partner and partner-to-C2CD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPAN16 grouped by C2CD6-low versus C2CD6-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD6→partner) and Y-score (partner→C2CD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TSPAN16 →	+0.054	+4.479	<.001	<.001	3	1
LUNG_NSCLC_LUAD	PNLIPRP3 →	+0.882	+4.857	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR13C3 →	+0.014	+3.887	<.001	.002	3	1
LUNG_NSCLC_LUAD	OOSP4B →	+0.011	+4.266	<.001	.004	3	1
SKIN	C19orf18 →	+0.213	+3.374	<.001	.005	3	1
CNS	RHO →	+0.032	+4.247	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 141 associations by consensus.

TSPAN16 by C2CD6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →