C2CD4C

Across TCGA patient cohorts, C2CD4C mutation is significantly associated with the RNA expression of many other genes, with 71 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2CD4C-associated genes across cancer lineages are KPNA2P1, H4C13, and RN7SL726P. Each is linked with C2CD4C in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD4C-to-partner and partner-to-C2CD4C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KPNA2P1 grouped by C2CD4C-low versus C2CD4C-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD4C→partner) and Y-score (partner→C2CD4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	KPNA2P1 →	+0.074	+4.378	<.001	.006	3	2
LIHC	H4C13 →	+0.517	+4.776	<.001	.003	3	1
UCEC	RN7SL726P →	+0.255	+4.073	.001	.004	3	1
UCEC	MIR6129 →	+0.808	+4.496	<.001	.002	3	1
COAD	MIR345 →	+0.703	+4.295	.001	.008	3	1
COAD	RNU6-784P →	+0.317	+4.516	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

KPNA2P1 by C2CD4C expression — LIHC

Explore this box plot interactively →