Q-omics provides the consensus-scored MIR345 profile across patient tissues and cancer cell-line models. MIR345 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in OV. Among the 18 cancer types available for tumor–normal comparison, MIR345 is differentially expressed in 5, with the highest sampling consensus in KIRC. Additionally, MIR345 RNA expression shows 11,316 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight OV, KIRC, and THYM as cancer lineages where MIR345 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR345 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR345 survival associations across molecular data types. MIR345 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR345 RNA expression–survival associations across cancer types. High MIR345 expression shows unfavorable associations in SKCM, CESC and UVM, but favorable associations in OV, LAML and HNSC. The OV Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .007). Together, the overview and detailed table identify OV as the clearest survival context for MIR345 RNA expression.
This table summarizes MIR345 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR345. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR345 shows lower tumor expression in KIRC, THCA, KIRP and KICH and higher tumor expression in LUSC. The KIRC box plot shows higher MIR345 RNA expression in normal versus tumor tissue (log2 FC = −0.298, t-test p < 0.001).
This table shows molecular features associated with MIR345 in patient tissues and cancer cell lines. In patient samples, MIR345 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
