C21orf91-OT1

Across TCGA patient cohorts, C21orf91-OT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,898 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C21orf91-OT1-associated GO terms across cancer lineages are Immune system development, Regulation of viral process, and JNK cascade. Each is linked with C21orf91-OT1 in more than 18 cancer types. Because this analysis shows association rather than direction, both C21orf91-OT1-to-partner and partner-to-C21orf91-OT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immune system development grouped by C21orf91-OT1-low versus C21orf91-OT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C21orf91-OT1→partner) and Y-score (partner→C21orf91-OT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Immune system development →	+0.050	+0.096	<.001	<.001	3	19
ESCA	Regulation of viral process →	+0.073	+0.233	<.001	<.001	2	19
ESCA	JNK cascade →	+0.059	+0.226	<.001	<.001	3	18
STAD	Sex-chromosome dosage compensation →	+0.059	+0.104	<.001	<.001	3	18
STAD	Antigen receptor-mediated signaling pathway →	+0.061	+0.100	<.001	<.001	3	18
STAD	Positive regulation of adaptive immune response →	+0.042	+0.099	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,898 associations by consensus.

Immune system development by C21orf91-OT1 expression — STAD

Explore this box plot interactively →