C20orf173

Across TCGA patient cohorts, C20orf173 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,653 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C20orf173-associated GO terms across cancer lineages are Regulation of mitochondrion organization, Positive regulation of plasma membrane bounded cell projection assembly, and Positive regulation of DNA metabolic process. Each is linked with C20orf173 in more than 18 cancer types. Because this analysis shows association rather than direction, both C20orf173-to-partner and partner-to-C20orf173 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrion organization grouped by C20orf173-low versus C20orf173-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf173→partner) and Y-score (partner→C20orf173) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of mitochondrion organization →	+0.071	+0.219	<.001	<.001	3	19
STAD	Positive regulation of plasma membrane bounded cell projection assembly →	+0.060	+0.218	<.001	<.001	3	19
STAD	Positive regulation of DNA metabolic process →	+0.064	+0.241	<.001	<.001	3	18
STAD	Protein localization to vacuole →	+0.067	+0.213	<.001	<.001	3	18
LAML	Obsolete histone methylation →	+0.079	+0.327	<.001	<.001	3	18
STAD	Regulation of telomere maintenance →	+0.070	+0.238	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,653 associations by consensus.

Regulation of mitochondrion organization by C20orf173 expression — ESCA

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