C20orf173

Across TCGA pan-cancer cohorts, C20orf173 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated C20orf173 data layer compared with 1 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher C20orf173 RNA is associated with better overall survival. In most high-consensus cancer types, elevated C20orf173 expression acts as an unfavorable survival marker, although some lineages such as BRCA and MESO show a favorable association.

BRCA, ACC, and MESO are the cancer types where C20orf173 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.960	0.912	.003	48	view →
ACC	DFS	Tertile	All	0.485	0.711	.005	30	view →
MESO	OS	Tertile	IV	0.850	0.269	.007	18	view →
LIHC	OS	Tertile	III,IV	1.000	0.314	.030	15	view →
LUAD	DFS	Tertile	III,IV	0.886	0.437	.039	12	view →
BLCA	DFS	Tertile	III,IV	0.296	0.519	.010	9	view →
HNSC	OS	Quartile	III,IV	0.510	0.284	.014	9	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	9	view →
COAD	OS	Tertile	III,IV	0.154	0.550	.029	9	view →
ESCA	OS	Median	III,IV	0.544	0.326	.023	5	view →
SCLC	DFS	Tertile	All	0.748	0.475	.017	4	view →
LGG	DFS	Tertile	All	0.757	0.874	.023	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

C20orf173–BRCA (OS)

Open the BRCA breakdown →