C20orf173

Across TCGA patient cohorts, C20orf173 protein abundance is significantly associated with the RNA expression of many other genes, with 150 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C20orf173-associated genes across cancer lineages are DOK5, SLC35F2, and WLS. Each is linked with C20orf173 in more than 1 cancer types. Because this analysis shows association rather than direction, both C20orf173-to-partner and partner-to-C20orf173 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C20orf173 versus DOK5 in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf173→partner) and Y-score (partner→C20orf173) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DOK5 →	+0.704	+0.571	.001	.005	3	1
GBM	SLC35F2 →	+0.835	+0.622	<.001	.001	3	1
GBM	WLS →	+0.810	+0.775	<.001	.004	3	1
GBM	NR5A2 →	+0.698	+0.800	.004	.004	3	1
GBM	MYRF →	-1.975	-0.783	.003	.007	3	1
GBM	TMCC2 →	-1.286	-0.586	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 150 associations by consensus.

C20orf173 vs DOK5 — GBM

Explore this scatter interactively →