C20orf173

Across TCGA cell cohorts, C20orf173 RNA expression is significantly associated with the go_rna of many other GO terms, with 461 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C20orf173-associated GO terms across cancer lineages are Base-excision repair, gap-filling, Transcription pausing by RNA polymerase II, and Bile acid metabolic process. Each is linked with C20orf173 in more than 4 cancer types. Because this analysis shows association rather than direction, both C20orf173-to-partner and partner-to-C20orf173 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair, gap-filling grouped by C20orf173-low versus C20orf173-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf173→partner) and Y-score (partner→C20orf173) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Base-excision repair, gap-filling →	+0.076	+0.013	.008	.008	3	5
LUNG_NSCLC_LUAD	Transcription pausing by RNA polymerase II →	+0.071	+0.025	.004	.005	2	5
OVARY	Bile acid metabolic process →	+0.101	+0.011	<.001	.001	3	4
PANCREAS	tRNA splicing, via endonucleolytic cleavage and ligation →	-0.078	-0.011	<.001	<.001	3	4
LIVER	Regulation of centrosome duplication →	+0.062	+0.020	.005	.004	3	4
LIVER	Regulation of centrosome cycle →	+0.059	+0.020	.008	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 461 associations by consensus.

Base-excision repair, gap-filling by C20orf173 expression — LIVER

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