C20orf141

Across TCGA patient cohorts, C20orf141 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C20orf141-associated genes across cancer lineages are MIR337, RNU6-597P, and COX6CP5. Each is linked with C20orf141 in more than 1 cancer types. Because this analysis shows association rather than direction, both C20orf141-to-partner and partner-to-C20orf141 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR337 grouped by C20orf141-low versus C20orf141-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf141→partner) and Y-score (partner→C20orf141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR337 →	+0.504	+6.438	<.001	.001	3	1
LUSC	RNU6-597P →	+0.353	+5.093	.001	.008	3	1
LUSC	COX6CP5 →	+0.193	+6.309	<.001	.001	3	1
LUSC	TPRX1P1 →	+0.189	+5.978	.002	.002	3	1
UCEC	MIR31 →	+0.745	+5.852	<.001	.003	3	1
UCEC	RNU6-1020P →	+0.940	+5.420	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

MIR337 by C20orf141 expression — LUSC

Explore this box plot interactively →