Across TCGA cell cohorts, C1orf68 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C1orf68-associated genes across cancer lineages are CSN1S1, OR2T10, and KRTAP20-2. Each is linked with C1orf68 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf68-to-partner and partner-to-C1orf68 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf68→partner) and Y-score (partner→C1orf68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CSN1S1 →	+0.034	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR2T10 →	+0.012	+5.228	.005	.005	3	1
LUNG_NSCLC_LUAD	KRTAP20-2 →	+0.155	+4.887	.005	.009	3	1
LARGE_INTESTINE	MMP26 →	+0.048	+4.217	<.001	.001	3	1
LARGE_INTESTINE	MYH13 →	+0.597	+4.054	<.001	.004	3	1
SKIN	CRX →	+0.005	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

C1orf68 survival (RNA) · tumor vs normal (RNA) · all C1orf68 data types