C1orf35

Across TCGA patient cohorts, C1orf35 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,108 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf35-associated proteins across cancer lineages are SMARCA5, CDC73, and CTR9. Each is linked with C1orf35 in more than 7 cancer types. Because this analysis shows association rather than direction, both C1orf35-to-partner and partner-to-C1orf35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf35 versus SMARCA5 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf35→partner) and Y-score (partner→C1orf35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SMARCA5 →	+0.338	+0.580	<.001	<.001	3	8
GBM	CDC73 →	+0.372	+0.450	<.001	<.001	3	8
GBM	CTR9 →	+0.258	+0.467	<.001	<.001	3	8
UCEC	PARP1 →	+0.504	+1.167	<.001	<.001	3	8
LSCC	RFC2 →	+0.467	+0.693	<.001	<.001	3	7
UCEC	CACYBP →	+0.417	+1.055	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,108 associations by consensus.

C1orf35 vs SMARCA5 — BRCA

Explore this scatter interactively →