C1orf35

Across TCGA patient cohorts, C1orf35 protein abundance is significantly associated with the RNA expression of many other genes, with 18,130 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf35-associated genes across cancer lineages are CKS1B, UTP25, and KIF14. Each is linked with C1orf35 in more than 9 cancer types. Because this analysis shows association rather than direction, both C1orf35-to-partner and partner-to-C1orf35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf35 versus CKS1B in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf35→partner) and Y-score (partner→C1orf35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CKS1B →	+0.911	+0.290	<.001	<.001	3	10
LSCC	UTP25 →	+0.662	+0.514	<.001	<.001	3	9
GBM	KIF14 →	+1.340	+0.498	<.001	<.001	3	9
LSCC	C1orf131 →	+0.599	+0.477	<.001	<.001	3	9
HNSC	TFB2M →	+0.756	+0.321	<.001	<.001	3	9
LSCC	SNRPE →	+0.749	+0.493	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,130 associations by consensus.

C1orf35 vs CKS1B — UCEC

Explore this scatter interactively →