C1orf35

Across TCGA patient cohorts, C1orf35 protein abundance is significantly associated with the protein abundance of many other proteins, with 31,428 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf35-associated proteins across cancer lineages are SAP18, SF3A1, and SF3A2. Each is linked with C1orf35 in more than 9 cancer types. Because this analysis shows association rather than direction, both C1orf35-to-partner and partner-to-C1orf35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf35 versus SAP18 in GBM, with a Pearson correlation of 0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf35→partner) and Y-score (partner→C1orf35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAP18 →	+0.351	+0.471	<.001	<.001	3	10
GBM	SF3A1 →	+0.323	+0.563	<.001	<.001	3	10
GBM	SF3A2 →	+0.343	+0.457	<.001	<.001	3	10
GBM	SNRPB2 →	+0.330	+0.465	<.001	<.001	3	10
HNSC	SRSF2 →	+0.299	+0.480	<.001	<.001	3	10
GBM	TPR →	+0.279	+0.496	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 31,428 associations by consensus.

C1orf35 vs SAP18 — GBM

Explore this scatter interactively →