C1orf21

Across TCGA cell cohorts, C1orf21 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,538 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C1orf21-associated GO terms across cancer lineages are Protein-lipid complex organization, Negative regulation of hydrogen peroxide biosynthetic process, and Basal dendrite development. Each is linked with C1orf21 in more than 5 cancer types. Because this analysis shows association rather than direction, both C1orf21-to-partner and partner-to-C1orf21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-lipid complex organization grouped by C1orf21-low versus C1orf21-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf21→partner) and Y-score (partner→C1orf21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Protein-lipid complex organization →	-0.076	-2.465	<.001	.003	3	6
SOFT_TISSUE	Negative regulation of hydrogen peroxide biosynthetic process →	+0.166	+1.394	<.001	<.001	3	6
URINARY_TRACT	Basal dendrite development →	-0.132	-1.114	.008	.004	3	6
URINARY_TRACT	Basal dendrite morphogenesis →	-0.132	-1.114	.008	.004	3	6
URINARY_TRACT	Basal dendrite arborization →	-0.132	-1.114	.008	.004	3	6
BLOOD_Lymphoma	Host-mediated perturbation of viral genome replication →	+0.055	+2.123	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,538 associations by consensus.

Protein-lipid complex organization by C1orf21 expression — BLOOD_Myeloma

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