C1orf115

Across TCGA patient cohorts, C1orf115 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C1orf115-associated genes across cancer lineages are TRBV20OR9-2, MIR646, and MIR212. Each is linked with C1orf115 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf115-to-partner and partner-to-C1orf115 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRBV20OR9-2 grouped by C1orf115-low versus C1orf115-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf115→partner) and Y-score (partner→C1orf115) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRBV20OR9-2 →	+0.471	+5.357	<.001	.006	3	1
COAD	MIR646 →	+0.460	+5.212	.001	.007	3	1
COAD	MIR212 →	+0.428	+6.122	<.001	.002	3	1
SKCM	VDAC2P4 →	+0.063	+4.076	.002	.001	3	1
SKCM	FAM138A →	+0.020	+5.219	<.001	.002	3	1
SKCM	SNORD13P3 →	+0.465	+3.915	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

TRBV20OR9-2 by C1orf115 expression — COAD

Explore this box plot interactively →