C1QTNF9

Across TCGA patient cohorts, C1QTNF9 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C1QTNF9-associated genes across cancer lineages are PEA-15, Smac, and Tuberin. Each is linked with C1QTNF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF9-to-partner and partner-to-C1QTNF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PEA-15 grouped by C1QTNF9-low versus C1QTNF9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF9→partner) and Y-score (partner→C1QTNF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PEA-15 →	-0.159	-2.459	.036	.020	3	1
SKCM	Smac →	-0.277	-2.442	.032	.020	3	1
SKCM	Tuberin →	+0.362	+2.459	.020	.020	3	1
SKCM	Caspase-8 →	-0.151	-2.321	.030	.033	3	1
UCEC	Notch1 →	+0.260	+3.013	<.001	.018	3	1
UCEC	STAT3_pY705 →	-0.450	-3.169	.001	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

PEA-15 by C1QTNF9 expression — SKCM

Explore this box plot interactively →