C1QTNF9

Across TCGA pan-cancer cohorts, C1QTNF9 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of C1QTNF9’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where C1QTNF9 RNA is repressed in tumor relative to normal tissue. In most cancer types C1QTNF9 is over-expressed in tumor, although a few such as COAD and BLCA show the opposite, repressed pattern.

COAD, BLCA, and THCA are the cancer types where C1QTNF9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C1QTNF9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	−0.701	<.001	10	view →
BLCA	All	III,IV	−1.018	<.001	9	view →
THCA	All	All	−0.117	<.001	9	view →
KICH	Female	All	−0.531	<.001	8	view →
LUSC	Male	II,III,IV	−0.417	<.001	8	view →
READ	All	All	−1.088	<.001	7	view →
LUAD	All	II,III,IV	−0.324	<.001	7	view →
KIRP	All	All	−0.225	<.001	7	view →
BRCA	All	III,IV	−1.878	<.001	6	view →
UCEC	All	All	−0.749	<.001	6	view →
HNSC	Male	All	−0.275	.013	5	view →
STAD	All	All	−0.318	.006	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

C1QTNF9–COAD

Open the COAD breakdown →