C1QTNF9

Across TCGA pan-cancer cohorts, C1QTNF9 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated C1QTNF9 data layer compared with 7 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher C1QTNF9 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C1QTNF9 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUAD show a favorable association.

UVM, BRCA, and LUAD are the cancer types where C1QTNF9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.564	0.898	.003	52	view →
BRCA	OS	Median	III,IV	0.661	0.428	<.001	48	view →
LUAD	OS	Median	All	0.435	0.253	<.001	46	view →
KIRC	OS	Tertile	All	0.690	0.531	.001	41	view →
LGG	DFS	Median	All	0.297	0.452	<.001	37	view →
PAAD	DFS	Tertile	All	0.477	0.255	.006	35	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	32	view →
THCA	DFS	Tertile	IV	0.859	0.399	.002	21	view →
LIHC	DFS	Quartile	All	0.498	0.178	.001	19	view →
SARC	OS	Tertile	All	0.811	0.567	.003	15	view →
MESO	DFS	Median	III,IV	0.451	0.288	.013	12	view →
COAD	OS	Median	IV	0.570	0.329	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

C1QTNF9–UVM (OS)

Open the UVM breakdown →