C1QTNF1

Across TCGA patient cohorts, C1QTNF1 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1QTNF1-associated genes across cancer lineages are ATM, Cyclin-B1, and JNK2. Each is linked with C1QTNF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1QTNF1-to-partner and partner-to-C1QTNF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by C1QTNF1-low versus C1QTNF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF1→partner) and Y-score (partner→C1QTNF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.486	-2.584	.002	.010	3	3
UCEC	Cyclin-B1 →	+0.698	+3.584	<.001	.002	3	3
UCEC	JNK2 →	+0.167	+2.348	.019	.018	3	2
UCEC	Notch1 →	+0.194	+2.428	<.001	.001	3	2
UCEC	p62 Lck ligand →	+0.477	+2.807	<.001	<.001	3	2
UCEC	eEF2 →	+0.280	+1.700	.029	.042	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

ATM by C1QTNF1 expression — UCEC

Explore this box plot interactively →