C1QTNF1

Across TCGA cell cohorts, C1QTNF1 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1QTNF1-associated genes across cancer lineages are TINAG, LYZL2, and C12orf40. Each is linked with C1QTNF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF1-to-partner and partner-to-C1QTNF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TINAG grouped by C1QTNF1-low versus C1QTNF1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF1→partner) and Y-score (partner→C1QTNF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TINAG →	+1.453	+3.807	<.001	.006	3	1
LUNG_SCLC	LYZL2 →	+0.016	+4.058	<.001	.007	3	1
LUNG_SCLC	C12orf40 →	+0.028	+3.736	<.001	.007	3	1
LUNG_SCLC	ACSM2A →	+0.022	+3.523	<.001	.008	3	1
LUNG_SCLC	KRTAP19-2 →	+0.102	+4.058	<.001	.007	3	1
LUNG_SCLC	CCL16 →	+0.043	+4.169	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

TINAG by C1QTNF1 expression — LUNG_SCLC

Explore this box plot interactively →