C1QA

Across TCGA cell cohorts, C1QA RNA expression is significantly associated with the go_rna of many other GO terms, with 1,082 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C1QA-associated GO terms across cancer lineages are Leukocyte mediated immunity, Glial cell activation, and Geranyl diphosphate metabolic process. Each is linked with C1QA in more than 3 cancer types. Because this analysis shows association rather than direction, both C1QA-to-partner and partner-to-C1QA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leukocyte mediated immunity grouped by C1QA-low versus C1QA-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QA→partner) and Y-score (partner→C1QA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Leukocyte mediated immunity →	+0.054	+0.030	<.001	.008	3	4
BLOOD_Leukemia	Glial cell activation →	+0.082	+0.110	.006	.003	3	4
SKIN	Geranyl diphosphate metabolic process →	+0.064	+0.033	.005	.003	3	4
SKIN	Mitochondrial tRNA methylation →	+0.076	+0.063	.001	<.001	3	4
SKIN	Centriole replication →	-0.046	-0.057	.005	.001	3	4
BREAST	Negative regulation of fat cell differentiation →	-0.074	-0.031	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,082 associations by consensus.

Leukocyte mediated immunity by C1QA expression — SKIN

Explore this box plot interactively →