C1QA

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C1QA mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1QA-associated genes across cancer lineages are MINAR2. Each is linked with C1QA in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QA-to-partner and partner-to-C1QA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MINAR2 grouped by C1QA-low versus C1QA-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QA→partner) and Y-score (partner→C1QA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMINAR2 →+0.048+4.882<.001<.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MINAR2 by C1QA expression — LARGE_INTESTINE

Box plot of MINAR2 in C1QA-low vs C1QA-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration