C1GALT1C1

Across TCGA patient cohorts, C1GALT1C1 mutation is significantly associated with the RNA expression of many other genes, with 1,681 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1GALT1C1-associated genes across cancer lineages are MTATP6P30, LINC01241, and FAM8A2P. Each is linked with C1GALT1C1 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1GALT1C1-to-partner and partner-to-C1GALT1C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTATP6P30 grouped by C1GALT1C1-low versus C1GALT1C1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1GALT1C1→partner) and Y-score (partner→C1GALT1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTATP6P30 →	+0.064	+7.930	<.001	.008	3	3
CESC	LINC01241 →	+0.233	+5.201	<.001	.007	3	2
CESC	FAM8A2P →	+0.050	+5.539	<.001	.004	3	2
UCEC	TGM7 →	+1.033	+2.959	<.001	<.001	3	2
UCEC	OR10A3 →	+0.054	+2.158	<.001	.001	3	2
LUSC	RNU6-289P →	+0.375	+3.324	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,681 associations by consensus.

MTATP6P30 by C1GALT1C1 expression — LUAD

Explore this box plot interactively →