C19orf57

Across TCGA patient cohorts, C19orf57 mutation is significantly associated with the RNA expression of many other genes, with 4,010 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C19orf57-associated genes across cancer lineages are LINC02876, HCAR1, and TSPY26P. Each is linked with C19orf57 in more than 2 cancer types. Because this analysis shows association rather than direction, both C19orf57-to-partner and partner-to-C19orf57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02876 grouped by C19orf57-low versus C19orf57-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf57→partner) and Y-score (partner→C19orf57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC02876 →	+0.142	+4.881	<.001	.002	3	3
UCEC	HCAR1 →	-0.490	-2.437	.002	.002	3	3
UCEC	TSPY26P →	-0.703	-2.502	.001	.001	3	3
HNSC	HMGB1P25 →	+0.142	+5.266	<.001	.001	3	2
HNSC	LINC01653 →	+0.066	+4.221	.001	.009	3	2
HNSC	DNAJC19P8 →	+0.232	+4.685	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,010 associations by consensus.

LINC02876 by C19orf57 expression — HNSC

Explore this box plot interactively →