C19orf47

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C19orf47 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C19orf47-associated genes across cancer lineages are REG3G, C20orf85, and ANKRD30BL. Each is linked with C19orf47 in more than 1 cancer types. Because this analysis shows association rather than direction, both C19orf47-to-partner and partner-to-C19orf47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG3G grouped by C19orf47-low versus C19orf47-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf47→partner) and Y-score (partner→C19orf47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaREG3G →+0.026+4.867.004.00931
BLOOD_LeukemiaC20orf85 →+0.027+3.969<.001.00931
BLOOD_LeukemiaANKRD30BL →+0.648+3.289<.001.00931
BLOOD_LeukemiaSPACA5 →+0.131+3.745<.001.00531
BLOOD_LeukemiaPROP1 →+0.027+3.289<.001.00931
BLOOD_LeukemiaTMEM270 →+0.044+4.661<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

REG3G by C19orf47 expression — BLOOD_Lymphoma

Box plot of REG3G in C19orf47-low vs C19orf47-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration