C19orf47

Across TCGA pan-cancer cohorts, C19orf47 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of C19orf47’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where C19orf47 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C19orf47 is over-expressed in tumor, although a few such as THCA and PRAD show the opposite, repressed pattern.

COAD, THCA, and LIHC are the cancer types where C19orf47 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C19orf47 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.603	<.001	10	view →
THCA	All	II,III,IV	−0.276	<.001	10	view →
LIHC	Female	II,III,IV	+0.988	<.001	9	view →
STAD	Male	II,III,IV	+0.699	<.001	8	view →
LUSC	Female	All	+0.882	<.001	7	view →
UCEC	All	All	+0.511	<.001	6	view →
LUAD	All	III,IV	+0.454	.002	6	view →
BRCA	All	All	+0.249	.001	6	view →
BLCA	Female	All	+0.646	.024	4	view →
HNSC	All	II,III,IV	+0.265	.012	4	view →
CHOL	Male	All	+1.530	<.001	3	view →
ESCA	All	All	+0.802	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

C19orf47–COAD

Open the COAD breakdown →