C19orf44

Across TCGA patient cohorts, C19orf44 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C19orf44-associated genes across cancer lineages are eEF2, Caspase-7-cleavedD198, and ERK2. Each is linked with C19orf44 in more than 2 cancer types. Because this analysis shows association rather than direction, both C19orf44-to-partner and partner-to-C19orf44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by C19orf44-low versus C19orf44-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf44→partner) and Y-score (partner→C19orf44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eEF2 →	+0.308	+2.178	.027	.035	3	3
COAD	Caspase-7-cleavedD198 →	+1.445	+3.016	<.001	.018	3	3
UCEC	ERK2 →	+0.128	+2.000	.047	.009	3	3
UCEC	A-Raf_pS299 →	-0.128	-2.415	.001	.003	3	2
UCEC	MEK1 →	+0.302	+2.584	.013	.001	3	2
UCEC	MSH2 →	-0.202	-1.848	.008	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

eEF2 by C19orf44 expression — COAD

Explore this box plot interactively →