C18orf12

Across TCGA patient cohorts, C18orf12 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,089 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C18orf12-associated proteins across cancer lineages are PPP6C, VSNL1, and GPC1. Each is linked with C18orf12 in more than 3 cancer types. Because this analysis shows association rather than direction, both C18orf12-to-partner and partner-to-C18orf12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C18orf12 versus PPP6C in LUAD, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf12→partner) and Y-score (partner→C18orf12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPP6C →	-0.171	-0.297	<.001	.005	3	4
UCEC	VSNL1 →	+0.980	+1.006	.003	.004	3	4
LSCC	GPC1 →	+0.718	+0.937	<.001	<.001	3	4
HNSC	HLA-F →	-0.641	-0.951	<.001	<.001	3	4
PDAC	PHLDA3 →	+0.521	+0.527	<.001	.001	3	3
LSCC	PSMB8 →	-0.258	-1.136	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,089 associations by consensus.

C18orf12 vs PPP6C — LUAD

Explore this scatter interactively →