C17orf75

Across TCGA patient cohorts, C17orf75 mutation is significantly associated with the RNA expression of many other genes, with 398 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf75-associated genes across cancer lineages are TMEM248P1, RN7SL134P, and RNA5SP129. Each is linked with C17orf75 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf75-to-partner and partner-to-C17orf75 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM248P1 grouped by C17orf75-low versus C17orf75-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf75→partner) and Y-score (partner→C17orf75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TMEM248P1 →	+0.039	+5.837	<.001	.001	3	2
UCEC	RN7SL134P →	+0.136	+2.792	.004	.006	3	2
CESC	RNA5SP129 →	+0.414	+4.503	<.001	.005	3	2
CESC	RNA5SP369 →	+0.310	+4.539	<.001	.008	3	2
UCEC	CYCTP →	+0.225	+2.526	.007	.007	3	2
SKCM	MRPS33P3 →	+0.106	+5.097	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 398 associations by consensus.

TMEM248P1 by C17orf75 expression — CESC

Explore this box plot interactively →