Q-omics provides the consensus-scored RNA5SP129 profile across patient tissues and cancer cell-line models. RNA5SP129 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in LAML. Among the 18 cancer types available for tumor–normal comparison, RNA5SP129 is differentially expressed in 2, with the highest sampling consensus in ESCA. Additionally, RNA5SP129 RNA expression shows 8,573 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight LAML, ESCA, and THYM as cancer lineages where RNA5SP129 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNA5SP129 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNA5SP129 survival associations across molecular data types. RNA5SP129 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNA5SP129 RNA expression–survival associations across cancer types. High RNA5SP129 expression shows unfavorable associations in BLCA, DLBC, KIRC, READ and COAD, but favorable associations in LAML. The LAML Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify LAML as the clearest survival context for RNA5SP129 RNA expression.
This table summarizes RNA5SP129 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNA5SP129. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNA5SP129 shows lower tumor expression in ESCA and THCA. The ESCA box plot shows higher RNA5SP129 RNA expression in normal versus tumor tissue (log2 FC = −0.542, t-test p = .003).
This table shows molecular features associated with RNA5SP129 in patient tissues and cancer cell lines. In patient samples, RNA5SP129 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
