C16orf82

Across TCGA patient cohorts, C16orf82 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. COAD shows the largest number of these associations.

The most reproducible C16orf82-associated genes across cancer lineages are PCNA, INPP4B, and Ku80. Each is linked with C16orf82 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf82-to-partner and partner-to-C16orf82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by C16orf82-low versus C16orf82-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf82→partner) and Y-score (partner→C16orf82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.421	+3.000	<.001	.037	3	2
UCEC	INPP4B →	-0.434	-3.000	.020	.036	3	1
UCEC	Ku80 →	+0.324	+3.013	.017	.019	3	1
UCEC	Notch1 →	+0.235	+3.000	.003	.037	3	1
UCEC	STAT3_pY705 →	-0.500	-2.990	<.001	.036	3	1
COAD	PRDX1 →	+0.236	+2.832	.004	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

PCNA by C16orf82 expression — UCEC

Explore this box plot interactively →