C16orf82

Across TCGA pan-cancer cohorts, C16orf82 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated C16orf82 data layer compared with 3 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher C16orf82 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C16orf82 expression acts as an unfavorable survival marker, although some lineages such as HNSC and THCA show a favorable association.

KICH, KIRC, and ACC are the cancer types where C16orf82 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.053	0.924	<.001	108	view →
KIRC	OS	Quartile	All	0.452	0.671	<.001	104	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	45	view →
UCEC	OS	Tertile	All	0.883	0.937	.006	36	view →
BRCA	OS	Tertile	IV	0.306	0.674	.012	27	view →
LIHC	OS	Tertile	All	0.419	0.715	.003	27	view →
HNSC	OS	Tertile	III,IV	0.864	0.716	.011	15	view →
SKCM	OS	Tertile	All	0.707	0.810	.023	12	view →
THCA	DFS	Tertile	All	0.967	0.744	.024	9	view →
GBM	OS	Tertile	All	0.230	0.445	.009	9	view →
PAAD	OS	Quartile	II,III,IV	0.239	0.437	.016	6	view →
LGG	DFS	Median	All	0.470	0.354	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

C16orf82–KICH (DFS)

Open the KICH breakdown →