C16orf74

Across TCGA patient cohorts, C16orf74 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,655 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C16orf74-associated proteins across cancer lineages are ZNF185, TBC1D2, and ST6GAL1. Each is linked with C16orf74 in more than 4 cancer types. Because this analysis shows association rather than direction, both C16orf74-to-partner and partner-to-C16orf74 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C16orf74 versus ZNF185 in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf74→partner) and Y-score (partner→C16orf74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF185 →	+0.914	+1.442	<.001	<.001	3	5
UCEC	TBC1D2 →	+0.495	+0.708	<.001	<.001	3	5
HNSC	ST6GAL1 →	-0.755	-0.849	<.001	<.001	3	5
BRCA	C16orf74_T44 →	+0.635	+1.074	.005	.002	3	5
GBM	EGFR →	+1.006	+0.306	<.001	.007	3	5
LSCC	FAM171A1_S855 →	-0.641	-1.020	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,655 associations by consensus.

C16orf74 vs ZNF185 — LSCC

Explore this scatter interactively →