C16orf46

Across TCGA patient cohorts, C16orf46 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,169 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible C16orf46-associated GO terms across cancer lineages are Transport along microtubule, Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Vesicle targeting. Each is linked with C16orf46 in more than 32 cancer types. Because this analysis shows association rather than direction, both C16orf46-to-partner and partner-to-C16orf46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by C16orf46-low versus C16orf46-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf46→partner) and Y-score (partner→C16orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Transport along microtubule →	+0.076	+0.891	<.001	<.001	3	33
SCLC	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.061	+0.533	<.001	<.001	3	33
UCS	Vesicle targeting →	+0.064	+0.958	<.001	<.001	3	32
SCLC	Smoothened signaling pathway →	+0.057	+0.696	<.001	<.001	3	32
SCLC	Protein localization to cilium →	+0.053	+0.664	<.001	<.001	3	32
DLBC	Negative regulation of telomere maintenance via telomere lengthening →	+0.078	+0.566	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,169 associations by consensus.

Transport along microtubule by C16orf46 expression — SCLC

Explore this box plot interactively →