C16orf46

Across TCGA cell cohorts, C16orf46 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,961 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C16orf46-associated GO terms across cancer lineages are Protein localization to cilium, Transport along microtubule, and Regulation of organelle assembly. Each is linked with C16orf46 in more than 11 cancer types. Because this analysis shows association rather than direction, both C16orf46-to-partner and partner-to-C16orf46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by C16orf46-low versus C16orf46-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf46→partner) and Y-score (partner→C16orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein localization to cilium →	+0.060	+0.447	<.001	.005	3	12
LUNG_NSCLC_LUAD	Transport along microtubule →	+0.028	+0.426	.003	<.001	3	10
LARGE_INTESTINE	Regulation of organelle assembly →	+0.047	+0.572	<.001	<.001	3	10
STOMACH	Process utilizing autophagic mechanism →	+0.065	+0.551	<.001	<.001	3	10
STOMACH	Autophagy →	+0.065	+0.551	<.001	<.001	3	10
CNS	Protein localization to ciliary transition zone →	+0.064	+0.368	.001	.005	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,961 associations by consensus.

Protein localization to cilium by C16orf46 expression — OVARY

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