Across TCGA patient cohorts, C14orf180 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C14orf180-associated genes across cancer lineages are PABPC1L2B-AS1, PPIAL4E, and RNU7-196P. Each is linked with C14orf180 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf180-to-partner and partner-to-C14orf180 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf180→partner) and Y-score (partner→C14orf180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PABPC1L2B-AS1 →	+0.029	+5.660	<.001	.001	3	2
UCEC	PPIAL4E →	+0.082	+4.038	<.001	.004	3	1
SKCM	RNU7-196P →	+0.537	+7.816	<.001	.008	3	1
SKCM	RN7SKP157 →	+0.134	+7.816	<.001	.008	3	1
SKCM	RNA5SP200 →	+0.367	+7.816	<.001	.008	3	1
SKCM	OR7E154P →	+0.049	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

C14orf180 survival (RNA) · tumor vs normal (RNA) · all C14orf180 data types