Across TCGA patient cohorts, C14orf178 mutation is significantly associated with the RNA expression of many other genes, with 506 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C14orf178-associated genes across cancer lineages are LAMTOR1, YAF2, and HOMER1. Each is linked with C14orf178 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf178-to-partner and partner-to-C14orf178 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf178→partner) and Y-score (partner→C14orf178) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LAMTOR1 →	+0.451	+3.470	.005	.003	3	1
UCEC	YAF2 →	+0.398	+3.470	.009	.003	3	1
UCEC	HOMER1 →	+0.875	+3.459	.001	.005	3	1
UCEC	USP12 →	+0.694	+3.225	.001	.009	3	1
UCEC	SAR1B →	+0.564	+3.346	.002	.005	3	1
UCEC	VPS37A →	+0.672	+3.470	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 506 associations by consensus.

Exploration

C14orf178 survival (RNA) · tumor vs normal (RNA) · all C14orf178 data types