C12orf76

Across TCGA patient cohorts, C12orf76 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,978 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C12orf76-associated proteins across cancer lineages are PTPN11, P4HB, and RCOR3. Each is linked with C12orf76 in more than 5 cancer types. Because this analysis shows association rather than direction, both C12orf76-to-partner and partner-to-C12orf76 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf76 versus PTPN11 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf76→partner) and Y-score (partner→C12orf76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTPN11 →	+0.255	+0.534	<.001	<.001	3	5
GBM	P4HB →	-0.471	-0.320	<.001	<.001	3	5
LSCC	RCOR3 →	+0.312	+0.340	<.001	<.001	3	5
OV	SART3 →	+0.328	+0.501	.002	.005	2	6
GBM	ARPC5 →	-0.251	-0.310	<.001	<.001	3	5
BRCA	ACTR2 →	-0.194	-0.369	<.001	.006	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,978 associations by consensus.

C12orf76 vs PTPN11 — BRCA

Explore this scatter interactively →