C12orf75

Across TCGA patient cohorts, C12orf75 protein abundance is significantly associated with the RNA expression of many other genes, with 7,470 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C12orf75-associated genes across cancer lineages are ISCU, RHOBTB2, and USH1C. Each is linked with C12orf75 in more than 3 cancer types. Because this analysis shows association rather than direction, both C12orf75-to-partner and partner-to-C12orf75 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf75 versus ISCU in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf75→partner) and Y-score (partner→C12orf75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ISCU →	+0.306	+0.463	.001	<.001	3	4
BRCA	RHOBTB2 →	+0.716	+0.484	<.001	<.001	3	4
PDAC	USH1C →	+1.043	+0.466	.007	.005	3	4
GBM	PIK3IP1 →	+0.607	+0.403	.001	.001	3	3
OV	AKNA →	+0.824	+0.401	<.001	<.001	3	3
BRCA	KIF17 →	+0.475	+0.714	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,470 associations by consensus.

C12orf75 vs ISCU — GBM

Explore this scatter interactively →