C12orf75

Across TCGA cell cohorts, C12orf75 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,136 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C12orf75-associated GO terms across cancer lineages are Cold acclimation, Regulation of T-helper cell differentiation, and Positive regulation of dopamine uptake involved in synaptic transmission. Each is linked with C12orf75 in more than 14 cancer types. Because this analysis shows association rather than direction, both C12orf75-to-partner and partner-to-C12orf75 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cold acclimation grouped by C12orf75-low versus C12orf75-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf75→partner) and Y-score (partner→C12orf75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cold acclimation →	+0.163	+1.927	<.001	<.001	2	15
LIVER	Regulation of T-helper cell differentiation →	+0.162	+2.187	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of dopamine uptake involved in synaptic transmission →	+1.458	+2.812	<.001	<.001	3	11
URINARY_TRACT	PML body organization →	+0.185	+2.825	.004	.006	3	10
OESOPHAGUS	Regulation of systemic arterial blood pressure →	+0.168	+1.824	.003	.002	3	10
PANCREAS	Negative regulation of bone mineralization involved in bone maturation →	+1.312	+2.036	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,136 associations by consensus.

Cold acclimation by C12orf75 expression — BONE

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