C12orf71

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C12orf71 mutation is significantly associated with the RNA expression of many other genes, with 1,146 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C12orf71-associated genes across cancer lineages are FAM243B, P3R3URF-PIK3R3, and MIR3621. Each is linked with C12orf71 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf71-to-partner and partner-to-C12orf71 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf71→partner) and Y-score (partner→C12orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAFAM243B →+0.089+7.725<.001<.00132
BRCAP3R3URF-PIK3R3 →+0.054+5.575<.001.00432
COADMIR3621 →+0.531+5.917<.001.00132
BRCAIGHVII-46-1 →+0.894+5.230<.001.00732
HNSCRNU4-41P →+0.222+6.623<.001<.00132
HNSCTXNP3 →+0.266+4.372<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,146 associations by consensus.

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