Across TCGA patient cohorts, C12orf71 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C12orf71-associated genes across cancer lineages are C-Raf, EGFR_pY1068, and FoxM1. Each is linked with C12orf71 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf71-to-partner and partner-to-C12orf71 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf71→partner) and Y-score (partner→C12orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C-Raf →	+0.143	+2.459	.038	.020	3	2
UCEC	EGFR_pY1068 →	-0.295	-3.000	.014	.036	3	1
UCEC	FoxM1 →	+0.252	+3.584	.043	.002	3	1
UCEC	Notch1 →	+0.220	+2.459	.001	.020	3	1
UCEC	PCNA →	+0.253	+2.459	.015	.020	2	2
UCEC	STAT3_pY705 →	-0.495	-3.311	<.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

C12orf71 survival (RNA) · tumor vs normal (RNA) · all C12orf71 data types