Across TCGA pan-cancer cohorts, C12orf60 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C12orf60 data layer compared with 20 for mass-spec protein and 2 for mutation status.
The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher C12orf60 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated C12orf60 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.
LSCC are the cancer types where C12orf60 mass-spec protein most reproducibly stratifies survival.