C12orf60

Across TCGA patient cohorts, C12orf60 mutation is significantly associated with the RNA expression of many other genes, with 2,778 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C12orf60-associated genes across cancer lineages are CDY3P, MSRB1P1, and RNU6-937P. Each is linked with C12orf60 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf60-to-partner and partner-to-C12orf60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDY3P grouped by C12orf60-low versus C12orf60-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf60→partner) and Y-score (partner→C12orf60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDY3P →	+0.038	+5.468	<.001	.002	3	2
SKCM	MSRB1P1 →	+0.443	+3.765	<.001	.007	3	2
UCEC	RNU6-937P →	+0.445	+2.440	.001	<.001	3	2
SKCM	APOBEC1 →	+0.094	+4.075	<.001	.004	3	1
BLCA	RNU1-33P →	+0.415	+5.018	<.001	.004	3	1
SKCM	OR12D1 →	+0.037	+4.282	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,778 associations by consensus.

CDY3P by C12orf60 expression — HNSC

Explore this box plot interactively →