C12orf60

Across TCGA cell cohorts, C12orf60 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,746 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C12orf60-associated GO terms across cancer lineages are RNA modification, tRNA splicing, via endonucleolytic cleavage and ligation, and Mitochondrial tRNA processing. Each is linked with C12orf60 in more than 7 cancer types. Because this analysis shows association rather than direction, both C12orf60-to-partner and partner-to-C12orf60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA modification grouped by C12orf60-low versus C12orf60-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf60→partner) and Y-score (partner→C12orf60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	RNA modification →	+0.059	+0.820	<.001	<.001	3	8
CNS	tRNA splicing, via endonucleolytic cleavage and ligation →	+0.088	+0.677	<.001	<.001	3	7
CNS	Mitochondrial tRNA processing →	+0.108	+0.653	<.001	.001	3	7
LARGE_INTESTINE	Regulation of DNA damage checkpoint →	+0.051	+0.542	<.001	<.001	3	7
OVARY	Methylation →	+0.045	+0.582	.002	.001	3	6
OESOPHAGUS	Mitochondrial translation →	+0.091	+0.571	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,746 associations by consensus.

RNA modification by C12orf60 expression — CNS

Explore this box plot interactively →